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ClinVar contains an entry for this variant (Variation ID: 574387). Variants that disrupt the consensus splice internet site are a comparatively typical reason for aberrant splicing (PMID: 17576681, 9536098). Algorithms produced to forecast the influence of sequence changes on RNA splicing suggest this variant could make or fortify a splice web-site
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Consumers may have to consult a roofing supplier for just a shingle that’s designed for roofing apps, and they have to also check their area constructing codes to be certain they’re code compliant.Linking to some non-federal Internet site does not represent an endorsement by CDC or any of its workforce with the sponsors or the data and solution